Syphilis is a disease caused by a spirochete called Treponema pallidum (TP). If untreated, the organism moves across the body and can cause damage to many organs, making syphilis life-threatening diseases if not treated early fully. Serological response to syphilis involve the production of antibodies against various antigens, including non-specific antibodies and specific anti-TP antibody. The first response to infection is detected the production of specific anti-treponemal IgM, which can be detected within 4 to 7 days after the chancre appears and until the end of the second week of infection, anti-treponemal IgG appeared in about four weeks later. The symptoms of syphilis as the disease progresses, most patients have both IgG and IgM detected. Syphilis infection can spread through the bloodstream to all parts of the body. If untreated, syphilis can cause severe heart disease, brain damage, spinal cord damage, blindness, and death.
Syphilis is a public health problem in many persistent low-income countries that have limited capacity for testing, which has traditionally relied on non-treponemal tests are sensitive and specific treponemal tests. However, the development of new rapid treponemal tests provide opportunities to enhance syphilis screening in many settings where traditional tests are not available.
The reason you might not be able to perform the test or why the results can not be helpful include:
# The use of antibiotics before having the test.
# A blood transfusion in the weeks before a test.
# Has other conditions or diseases, like lupus, heart disease, HIV infection, or yaws.
Untreated syphilis infection during pregnancy can infect the baby.
The risk of infection was greatest when the mother has early stage syphilis.
If a pregnant woman to get treatment before the 16th week of pregnancy, the baby usually will not have syphilis.
Untreated infection during pregnancy can cause miscarriage, premature birth, stillbirth, or birth defects.
If a screening test is positive (reactive), the strength of the results can be determined by measuring the amount of reagin. These results are then given in titers. Titer is a measure of how many samples of blood or spinal fluid may be diluted before the reagin can no longer be detected. Reactive or positive test result does not necessarily mean that you have syphilis. Other conditions can cause positive screening test results, including drugs with needles, recent vaccinations, pregnancy, endocarditis, autoimmune diseases (such as systemic lupus erythematosus, or SLE), tuberculosis, mononucleosis, leprosy, malaria, hepatitis, Lyme disease, and rheumatoid arthritis.
Screening for syphilis and other sexually transmitted diseases (STDs) are often performed for people who engage in high risk sexual behavior. If you have syphilis, your sex partner or spouse must be notified, tested, and treated to prevent serious complications and to stop the spread of disease. With treatment, syphilis test result usually becomes negative. Positive treponemal (FTA-ABS, MHA-TP, TPPA) tests stay positive for life.
Sores caused by syphilis (chancres) make it easier to get and spread HIV infection.
People with HIV infection who tested negative VDRL should conduct a second test for syphilis if the infection is suspected.
Accurate and rapid diagnosis of sexually transmitted diseases (STDs) are major global public health priority, particularly in developing countries. Since the advent of HIV / AIDS, has become even more important to diagnose STDs early, not only to save lives but also to prevent the spread of life-threatening infections. The answer is technology accurate, easy and innovative dynamic performance from us to anywhere in the world. for dynamic performance anywhere in the world, for the dynamic performance anywhere in the world, allows detection of the causative organism of syphilis should be simple, accurate and in no time.
Syphilis rapid test kits are very sensitive and specific; With one step TP test, the results are read visually without any instrument; Syphilis immunoassay test kit is easy to operate; There is no other reagents needed to perform TP rapid test kits.
Two simple step test requires no electricity, water, minimal training, just for fingerstick sample collection and can be easily stored and transported.
Syphilis rapid test, also known as one step syphilis test, is a rapid direct binding test for visual detection of syphilis antibodies in human serum specimens in vitro, as an aid in the diagnosis of syphilis infection. Syphilis rapid test is based on the principle of double sandwich immunoassay for antigen detection of syphilis antibodies in human serum. With TP rapid test, purified recombinant syphilis antigens are used to identify antibodies specific syphilis. TP rapid test is very sensitive and only takes about 10 to 20 minutes to find out the results of screening. The results are easy to interpret with syphilis rapid diagnostic test kit: one pink line on the control area, the sample is negative, conversely, if two pink or red lines appear in the test area and control of each region, the sample tested is very likely to be positive.
Blood tests found antibodies the body makes to fight syphilis. A positive syphilis test can indicate current or previous infection. A blood test may not find antibodies to three months after exposure to bacteria. If you think you may have been exposed to syphilis, get another test in 6 months is recommended for confirmation. Antibodies stay in the body for many years, so if you have syphilis and treated before, you can still test positive. To avoid treated again, let your doctor know about previous infections and / or treatment.
A positive syphilis test shows that you have either current infection or past. However, a negative test does not necessarily mean that you do not have syphilis. It could take up to 3 months after exposure to syphilis for antibodies to be detected. If you're worried you have been exposed and negative tests, you should test again in 3 months for confirmation.
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